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Serving hundreds of leading biopharmaceutical companies globally:

Cipla
Mallinckrodt
Medtronic
Fuji
Argus Health
Cantor Fitzgerald
Teva
UBS
Harvard Business School

Generated: April 23, 2018

DrugPatentWatch Database Preview

Claims for Patent: 8,513,262

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Summary for Patent: 8,513,262
Title:Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
Abstract: A process for the preparation of a compound of formula (I) ##STR00001## comprising the steps: (a) reacting a compound of formula (II) ##STR00002## wherein L and L' are suitable leaving groups, with a compound of formula (III) UNH.sub.2 (III) to prepare a compound of formula (IV) ##STR00003## and subsequently (b) substituting the group R.sup.1 by replacement of the leaving group L'.
Inventor(s): Carter; Malcolm Clive (Ware, GB), Cockerill; George Stuart (Bedford, GB), Lackey; Karen Elizabeth (Hillsborough, NC)
Assignee: GlaxoSmithKline LLC (Philadelphia, PA)
Application Number:12/691,784
Patent Claims: 1. A compound of the formula ##STR00057## or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition, comprising a compound of claim 1, together with one or more of pharmaceutically acceptable carriers, diluents or excipients.

3. A pharmaceutical composition as claimed in claim 2 in unit dosage form.

4. A compound of the formula ##STR00058##

5. A pharmaceutical composition, comprising the compound of claim 4, together with one or more of pharmaceutically acceptable carriers, diluents or excipients.

6. A pharmaceutical composition as claimed in claim 5 in unit dosage form.

7. A pharmaceutically acceptable salt of the compound of the formula ##STR00059##

8. A pharmaceutical composition, comprising the compound of claim 7, together with one or more of pharmaceutically acceptable carriers, diluents or excipients.

9. A pharmaceutical composition as claimed in claim 7 in unit dosage form.

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Serving hundreds of leading biopharmaceutical companies globally:

Merck
Argus Health
Dow
UBS
Deloitte
Johnson and Johnson
Chubb
US Army
Queensland Health

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