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Claims for Patent: 8,440,170

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Claims for Patent: 8,440,170

Title:Orally disintegrating tablets with speckled appearance
Abstract: Orally disintegrating tablets containing colored granules of a water-soluble sugar which give them a speckled appearance are described. The orally disintegrating tablets with speckled appearance are readily and easy identifiable by physicians, nurses and patients.
Inventor(s): Stroppolo; Federico (Mezzovico, CH), Ardalan; Shahbaz (Mezzovico, CH)
Assignee: Alpex Pharma SA (Mezzovico, CH)
Application Number:12/811,737
Patent Claims: 1. An orally disintegrating tablets with speckled appearance comprising (a) speckles comprising colored granules of a water-soluble sugar, and (b) a pharmaceutically acceptable carrier.

2. The orally disintegrating tablets according to claim 1 wherein the water-soluble sugar is selected from the group consisting of sucrose and polyalcohols.

3. The orally disintegrating tablets according to claim 2 wherein the water-soluble sugar is selected from the group consisting of sucrose, sorbitol, mannitol, xylitol, and fructose.

4. The orally disintegrating tablets according to claim 3 wherein the water-soluble sugar is mannitol.

5. The orally disintegrating tablets according to claim 1 wherein the colored granules have a particle size from about 10 .mu.m to about 1200 .mu.m.

6. The orally disintegrating tablets according to claim 5 wherein the colored granules have a particle size from about 200 .mu.m to about 800 .mu.m.

7. The orally disintegrating tablets according to claim 6 wherein the colored granules have a particle size from about 300 .mu.m to about 500 .mu.m.

8. The orally disintegrating tablets according to claim 1 wherein the colored granules are present in an amount from about 0.1% w/w to about 50% w/w per tablet.

9. The orally disintegrating tablets according to claim 1 wherein the colored granules are present in an amount from about 1% w/w to about 30% w/w.
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