BioPharmaceutical Business Intelligence

  • Analyze global market entry opportunities
  • Identify first generic entrants
  • Uncover prior art in expired and abandoned patents

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

US Army
US Department of Justice
Daiichi Sankyo
Chinese Patent Office
Johnson and Johnson
Federal Trade Commission

Generated: November 18, 2017

DrugPatentWatch Database Preview

Claims for Patent: 8,377,916

« Back to Dashboard

Claims for Patent: 8,377,916

Title:Steroids as agonists for FXR
Abstract: The invention relates to compounds of formula (I): ##STR00001## wherein R is ethyl, propyl or allyl, and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR agonists.
Inventor(s): Pellicciari; Roberto (Perugia, IT)
Assignee: Intercept Pharmaceuticals, Inc. (New York, NY)
Application Number:13/288,558
Patent Claims: 1. A method for the treatment of cholestatic liver disease, atherosclerosis, arteriosclerosis, hypercholesteremia, or hyperlipidemia comprising administering a pharmaceutical composition comprising a therapeutically effective amount of a compound of formula (I) ##STR00007## or a pharmaceutically acceptable salt or amino acid conjugates thereof, wherein R is ethyl and at least one pharmaceutical carrier or diluent, wherein said compound is administered at 0.01 mg/kg to 100 mg/kg per dose.

2. The method of claim 1, wherein the composition is administered orally.

3. The method of claim 1, wherein the composition is administered as a single daily dose.

4. The method of claim 1, wherein the administration is the compound of formula I ##STR00008##
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Serving leading biopharmaceutical companies globally:

Daiichi Sankyo
Harvard Business School
Argus Health
US Department of Justice

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2017 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch:

Google Plus