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Generated: April 25, 2018

DrugPatentWatch Database Preview

Claims for Patent: 8,324,281

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Summary for Patent: 8,324,281
Title:Topical nepafenac formulations
Abstract: Topical suspension compositions of nepafenac are disclosed. The compositions are especially suitable for topical ophthalmic administration.
Inventor(s): Wong; Warren (Fort Worth, TX)
Assignee: Novartis AG (Basel, CH)
Application Number:13/253,648
Patent Claims: 1. A topically administrable ophthalmic composition consisting of a) 0.1% (w/v) nepafenac; b) 0.5% (w/v) carbomer; c) 0.001-0.05% (w/v) tyloxapol; d) 0.3-0.5% (w/v) sodium chloride; e) 2-3% (w/v) mannitol; f) a pH-adjusting agent in an amount sufficient to cause the composition to have a pH from 7.3-7.7; g) 0.001-0.01% (w/v) benzalkonium chloride; h) 0.001-0.1% (w/v) edetate disodium; and i) water.

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