You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: April 19, 2024

Claims for Patent: 8,268,791

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 8,268,791

Title:	Alkylglycoside compositions for drug administration
Abstract:	The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms.
Inventor(s):	Maggio; Edward T. (San Diego, CA)
Assignee:	Aegis Therapeutics, LLC. (San Diego, CA)
Application Number:	12/341,696
Patent Claims:	1. A pharmaceutical composition comprising: a) a triptan analog selected from sumatriptan, naratriptan, zolmitriptan, eletriptan, almotriptan, frovatriptan; and b) an absorption increasing amount of an alkylglycoside, wherein the alkylglycoside comprises a maltose linked by glycosidic linkage to an alkyl chain comprising between 12 to 16 carbons, and wherein the concentration of alkylglycoside is between 0.05% and 20% by weight. 2. The pharmaceutical composition of claim 1, wherein the triptan analog is sumatriptan. 3. The pharmaceutical composition of claim 1, wherein the alkylglycoside is selected from the group consisting of dodecyl maltoside, tridecyl maltoside, and tetradecyl maltoside. 4. The pharmaceutical composition of claim 3, wherein the alkylglycoside consists of tetradecyl-.beta.-D-maltoside. 5. The pharmaceutical composition of claim 3, wherein the alkylglycoside consists of dodecyl-.beta.-D-maltoside. 6. The pharmaceutical composition of claim 3, wherein the alkylglycoside consists of tridecyl-.beta.-D-maltoside. 7. The pharmaceutical composition of claim 1, wherein the triptan analog is sumatriptan. 8. The pharmaceutical composition of claim 1, wherein the triptan analog is naratriptan. 9. The pharmaceutical composition of claim 1, wherein the triptan analog is zolmitriptan. 10. The pharmaceutical composition of claim 1, wherein the triptan analog is eletriptan. 11. The pharmaceutical composition of claim 1, wherein the triptan analog is almotriptan. 12. The pharmaceutical composition of claim 1, wherein the triptan analog is frovatriptan. 13. The pharmaceutical composition of claim 1, wherein the alkylglycoside is dodecyl maltoside, and wherein the triptan analog is sumatriptan. 14. The pharmaceutical composition of claim 1, further comprising ethylenediaminetetraacetic acid (EDTA). 15. The pharmaceutical composition of claim 1, wherein the alkylglycoside is a .beta.-anomer.

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.