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Summary for Patent: 8,242,158
|Title:||Dexmedetomidine premix formulation|
|Abstract:||The presently disclosed subject matter relates to pharmaceutical compositions comprising dexmedetomidine or a pharmaceutically acceptable salt thereof wherein the composition is formulated as a liquid for parenteral administration to a subject, and wherein the composition is disposed within a sealed container as a premixture. The pharmaceutical compositions can be used, for example, in perioperative care of a patient or for sedation.|
|Inventor(s):||Roychowdhury; Priyanka (San Rafael, CA), Cedergren; Robert A. (Libertyville, IL)|
|Assignee:||Hospira, Inc. (Lake Forest, IL)|
|Patent Litigation and PTAB cases:||See patent lawsuits and PTAB cases for patent 8,242,158|
1. A ready to use liquid pharmaceutical composition for parenteral administration to a subject, comprising dexmedetomidine or a pharmaceutically acceptable salt thereof at a
concentration of about 4 .mu.g/mL disposed within a sealed glass container.
2. The ready to use liquid pharmaceutical composition of claim 1, further comprising sodium chloride at a concentration of between about 0.01 and about 2.0 weight percent.
3. The ready to use liquid pharmaceutical composition of claim 2, wherein the sodium chloride is present at a concentration of about 0.9 weight percent.
4. The ready to use liquid pharmaceutical composition of claim 1, wherein the composition is formulated as a total volume selected from the group consisting of 20 mL, 50 mL and 100 mL.
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