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Last Updated: April 19, 2024

Claims for Patent: 8,211,889


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Summary for Patent: 8,211,889
Title:Prodrugs of 2,4-pyrimidinediamine compounds and their uses
Abstract: The present disclosure provides prodrugs of biologically active 2,4-pyrimidinediamine compounds, compositions comprising the prodrugs, intermediates and methods for synthesizing the prodrugs and methods of using the prodrugs in a variety of applications.
Inventor(s): Singh; Rajinder (Belmont, CA), Bhamidipati; Somasekhar (Foster City, CA), Sun; Thomas (Fremont, CA), Stella; Valentino J. (Lawrence, KS)
Assignee: Rigel Pharmaceuticals, Inc. (South San Francisco, CA)
Application Number:13/349,194
Patent Claims: 1. A compound of the formula ##STR00030## or a pharmaceutically acceptable salt thereof, wherein the compound or pharmaceutically acceptable salt thereof is in the form of a hydrate.

2. The compound of claim 1, wherein the compound is a free acid.

3. The compound of claim 1, wherein the compound is a pharmaceutically acceptable salt.

4. The compound of claim 3, wherein the pharmaceutically acceptable salt is an alkali metal salt.

5. The compound of claim 4, wherein the pharmaceutically acceptable salt is a sodium salt.

6. The compound of claim 5, wherein the pharmaceutically acceptable salt is a disodium salt.

7. The compound of claim 3, wherein the pharmaceutically acceptable salt is an alkaline earth metal salt.

8. The compound of claim 7, wherein the pharmaceutically acceptable salt is a calcium salt.

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