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Last Updated: April 24, 2024

Claims for Patent: 8,188,146

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Summary for Patent: 8,188,146

Title:	Highly purified ethyl EPA and other EPA derivatives
Abstract:	A pharmaceutical preparation comprising EPA in an appropriately assimilable form where of all the fatty acids present in the preparation at least 90%, and preferably at least 95%, is in the form of EPA and where less than 5%, and preferably less than 3%, is in the form of DHA is provided.
Inventor(s):	Peet; Malcolm (Sheffield, GB), Vaddadi; Krishna S. (Melbourne, AU)
Assignee:	Amarin Corporation Plc. (Dublin, IE)
Application Number:	12/052,598
Patent Claims:	1. A pharmaceutical composition comprising one or more fatty acids, at least 95% of which are in the form of ethyl-eicosapentaenoic acid, wherein the composition contains no docosahexaenoic acid and the composition is present in a capsule. 2. The composition of claim 1 wherein the composition contains less than 3% of any fatty acid other than eicosapentaenoic acid. 3. The composition of claim 2 wherein the capsule is a gelatin capsule. 4. The composition of any one of claim 1, 2, or 3 wherein the ethyl-eicosapentaenoic acid is present in the composition in an amount of 250 mg to 1000 mg. 5. A pharmaceutical composition comprising 250 mg to 1000 mg of fatty acids at least 95% of which are in the form of ethyl eicosapentaenoic acid, wherein the composition contains no docosahexaenoic acid, and the composition is present in a capsule. 6. A pharmaceutical composition comprising 250 mg to 1000 mg of fatty acids at least 95% of which are in the form of ethyl-eicosapentaenoic acid, wherein the composition contains (a) less than 5% in aggregate of arachidonic acid and n-3 docosapentaenoic acid, and (b) no docosahexaenoic acid; and wherein the composition is present in a capsule. 7. The pharmaceutical composition of claim 5 wherein the composition contains arachidonic acid in an amount less than 3%, by weight, of said fatty acids. 8. The pharmaceutical composition of claim 6 wherein the composition contains docosapentaenoic acid in an amount less than 3%, by weight, of said fatty acids. 9. The pharmaceutical composition of claim 6 wherein the composition contains arachidonic acid and docosapentaenoic acid in an aggregate amount of less than 3%, by weight, of said fatty acids. 10. The pharmaceutical composition of claim 6 wherein the capsule comprises about 1000 mg of said composition.

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