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Last Updated: August 13, 2020

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Claims for Patent: 8,143,271

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Summary for Patent: 8,143,271
Title:Compounds and methods for kinase modulation, and indications therefor
Abstract: Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
Inventor(s): Ibrahim; Prabha N. (Mountain View, CA), Artis; Dean R. (Kensington, CA), Bremer; Ryan (Oakland, CA), Zhang; Chao (Moraga, CA), Zhang; Jiazhong (Foster City, CA), Tsai; James (Vallejo, CA), Hirth; Klaus-Peter (San Francisco, CA), Bollag; Gideon (Orinda, CA), Cho; Hanna (Oakland, CA)
Assignee: Plexxikon Inc. (Berkeley, CA)
Application Number:13/216,200
Patent Claims: 1. A compound of the formula: ##STR03472##

2. A pharmaceutical composition comprising the compound of claim 1, and a pharmaceutically acceptable carrier, diluent or excipient.

3. The pharmaceutical composition of claim 2 in unit dosage form.

4. The pharmaceutical composition of claim 3, wherein the unit dosage form is a tablet.

5. A pharmaceutically acceptable salt of the compound of the formula: ##STR03473##

6. A pharmaceutical composition comprising a pharmaceutically acceptable salt of claim 5, and a pharmaceutically acceptable carrier, diluent or excipient.

7. The pharmaceutical composition of claim 6 in unit dosage form.

8. The pharmaceutical composition of claim 7, wherein the unit dosage form is a tablet.

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Serving leading biopharmaceutical companies globally:

Harvard Business School
Medtronic
Baxter
Merck
Moodys
McKinsey

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