|Title:||Compounds and methods for kinase modulation, and indications therefor|
|Abstract:||Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.|
|Inventor(s):||Ibrahim; Prabha N. (Mountain View, CA), Artis; Dean R. (Kensington, CA), Bremer; Ryan (Oakland, CA), Zhang; Chao (Moraga, CA), Zhang; Jiazhong (Foster City, CA), Tsai; James (Vallejo, CA), Hirth; Klaus-Peter (San Francisco, CA), Bollag; Gideon (Orinda, CA), Cho; Hanna (Oakland, CA)|
|Assignee:||Plexxikon Inc. (Berkeley, CA)|
1. A compound of the formula: ##STR03472##
2. A pharmaceutical composition comprising the compound of claim 1, and a pharmaceutically acceptable carrier, diluent or excipient.
3. The pharmaceutical composition of claim 2 in unit dosage form.
4. The pharmaceutical composition of claim 3, wherein the unit dosage form is a tablet.
5. A pharmaceutically acceptable salt of the compound of the formula: ##STR03473##
6. A pharmaceutical composition comprising a pharmaceutically acceptable salt of claim 5, and a pharmaceutically acceptable carrier, diluent or excipient.
7. The pharmaceutical composition of claim 6 in unit dosage form.
8. The pharmaceutical composition of claim 7, wherein the unit dosage form is a tablet.
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