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Claims for Patent: 8,097,648

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Claims for Patent: 8,097,648

Title:Methods and compositions for use in treating cancer
Abstract: The invention provides methods and compositions for use in treating diseases associated with excessive cellular proliferation, such as cancer.
Inventor(s): Littlefield; Bruce A. (Andover, MA), Towle; Murray J. (Auburn, NH), Seletsky; Boris M. (Andover, MA), Yu; Melvin J. (Andover, MA), Zheng; Wanjun (Londonderry, NH)
Assignee: Eisai R&D Management Co., Ltd. (Tokyo, JP)
Application Number:11/282,505
Patent Claims: 1. A method of inhibiting growth of a tumor in a patient, said method comprising administering to said patient a compound of the structure: ##STR00006## or a pharmaceutically acceptable salt thereof, wherein said tumor is breast carcinoma, and wherein said compound or pharmaceutically acceptable salt is not co-administered with another pharmaceutically active agent.

2. The method of claim 1, wherein said compound or pharmaceutically acceptable salt is administered in a pharmaceutical composition comprising a pharmaceutically-acceptable carrier.

3. The method of claim 1, wherein said compound or pharmaceutically acceptable salt is administered by oral, topical, parenteral, or intravenous routes, or by injection or inhalation.

4. The method of claim 1, wherein said compound or pharmaceutically acceptable salt is administered in a controlled-release formulation.

5. The method of claim 1, wherein said method consists of administration of said compound or pharmaceutically acceptable salt, in a pharmaceutically acceptable carrier or diluent, to said patient.
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