.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 8,047,202

« Back to Dashboard

Claims for Patent: 8,047,202

Title:Nasal devices
Abstract: A nasal delivery device and a method of delivering substance to a nasal airway of a subject, can be used for mass treatment, especially mass vaccination. The delivery device can include an interface unit, as a replaceable unit, having at least one nosepiece unit for fitting to a respective nostril of a subject, a nozzle from which substance is in use delivered, and at least one delivery unit having a substance supply unit for delivering substance to the nozzle of the at least one nosepiece unit. The delivery device can also include an actuation unit for actuating the at least one delivery unit of the interface unit.
Inventor(s): Djupesland; Per Gisle (Oslo, NO)
Assignee: OptiNose AS (Oslo, NO)
Application Number:12/339,716
Patent Claims: 1. A nasal delivery device for delivering substance to a nasal airway of a subject, comprising: a disposable interface unit, comprising at least one nosepiece unit for fitting to a respective nostril of a subject, each nosepiece unit comprising a nozzle from which substance is in use delivered, a mouthpiece into which the subject in use exhales, and at least one delivery unit comprising a substance supply unit for delivering substance to the nozzle of the at least one nosepiece unit; and an actuation unit for actuating the at least one delivery unit of the interface unit in response to exhalation by the subject into the mouthpiece; wherein the interface unit is disposable separately of the actuation unit.

2. The delivery device of claim 1, wherein the interface unit comprises a single integral unit.

3. The delivery device of claim 1, wherein the interface unit is packaged in protective packaging.

4. A nasal delivery device for delivering substance to a nasal airway of a subject, comprising: a disposable interface unit, comprising (i) first and second nosepiece units for fitting to respective nostrils of a subject, each nosepiece unit comprising a nozzle from which substance is in use delivered, and (ii) first and second delivery units, each delivery unit comprising a substance supply unit for delivering substance to the nozzle of the respective nosepiece unit; and an actuation unit for actuating the delivery units of the interface unit in response to exhalation by the subject; wherein the interface unit is disposable separately of the actuation unit.

5. The delivery device of claim 1 or 4, wherein the substance supply unit comprises a substance pump unit for delivering substance, the substance pump unit including a chamber containing substance and a piston member which is movable in the chamber to deliver a flow of substance from the chamber, and wherein the substance comprises a liquid or a powder.

6. The delivery device of claim 1, wherein the mouthpiece is fluidly connected to the at least one nosepiece unit such as to provide an air flow therethrough on exhalation by the subject into the mouthpiece.

7. The delivery device of claim 1, wherein the at least one delivery unit includes a gas supply unit for supplying a gas flow through the at least one nosepiece unit, wherein the gas supply unit comprises a gas pump unit for delivering a gas flow, the gas pump unit comprising a cylinder and a piston member which is movable in the cylinder to deliver the gas flow through the at least one nosepiece unit, and wherein the at least one delivery unit is configured such that the gas supply unit initiates supply of the gas flow prior to actuation of the substance supply unit to deliver substance.

8. The delivery device of claim 1, wherein the actuation unit includes a gas supply unit for supplying a gas flow through the at least one nosepiece unit, and wherein the actuation unit is configured such that the gas supply unit initiates supply of the gas flow prior to actuation of the substance supply unit to deliver substance.

9. The delivery device of claim 1, wherein the actuation unit includes a detection unit for detecting exhalation by the subject, at least one drive unit for actuating the at least one delivery unit, and a control unit for actuating the at least one drive unit in response to detecting exhalation by the subject, and wherein the detection unit includes (i) a pressure sensor for detecting a pressure in the mouthpiece, and the control unit is configured to actuate the at least one drive unit in response to detection of a predeterminable pressure by the detection unit or (ii) a flow sensor for detecting a flow rate through the mouthpiece, and the control unit is configured to actuate the at least one drive unit in response to detection of a predeterminable flow rate by the detection unit.

10. The delivery device of claim 1, wherein the actuation unit includes at least one drive unit for actuating the at least one delivery unit, and a trigger mechanism for actuating the at least one drive unit in response to exhalation by the subject into the mouthpiece, and wherein the trigger mechanism is configured to actuate the at least one drive unit in response to generation of (i) a predeterminable pressure in the mouthpiece or (ii) a predeterminable flow rate through the mouthpiece.

11. The delivery device of claim 1, wherein the interface unit includes first and second nosepiece units for fitting to respective nostrils of the subject, and first and second delivery units, each including a substance supply unit for delivering substance through the respective nosepiece unit, and wherein the actuation unit is configured to actuate the first and second delivery units in succession such that substance is first delivered into one nasal cavity and subsequently into the other nasal cavity.

12. The delivery device of claim 1 or 4, comprising: a plurality of interface units attached to a belt such as to allow for successive attachment of the interface units to the actuation unit, and wherein the actuation unit is configured successively to provide the interface units thereto through use of the belt as a guide.

13. The delivery device of claim 4, wherein the actuation unit is configured to actuate the first and second delivery units in succession such that substance is first delivered into one nasal cavity and subsequently into the other nasal cavity.

14. The delivery device of claim 4, wherein the interface unit further comprises a mouthpiece into which the subject in use exhales, and wherein the mouthpiece is fluidly connected to the at least one nosepiece unit such as to provide an air flow therethrough on exhalation by the subject into the mouthpiece.

15. The delivery device of claim 4, wherein the delivery units each include a gas supply unit for supplying a gas flow through the respective nosepiece units, wherein the gas supply unit comprises a gas pump unit for delivering the gas flow, the gas pump unit comprising a cylinder and a piston member which is movable in the cylinder to deliver the gas flow through the respective nosepiece units, and wherein the delivery units are configured such that the gas supply unit initiates supply of the gas flow prior to actuation of the substance supply unit to deliver substance.

16. The delivery device of claim 4, wherein the actuation unit includes a gas supply unit for supplying a gas flow through the nosepiece units, and wherein the actuation unit is configured such that the gas supply unit initiates supply of the gas flow prior to actuation of the substance supply unit to deliver substance.

17. The delivery device of claim 4, wherein the actuation unit includes a detection unit for detecting exhalation by the subject, first and second drive units for actuating the first and second delivery units, and a control unit for actuating the drive units in response to detecting exhalation by the subject, and wherein the detection unit includes (i) a pressure sensor for detecting a pressure, and the control unit is configured to actuate the drive units in response to detection of a predeterminable pressure by the detection unit or (ii) a flow sensor for detecting a flow rate, and the control unit is configured to actuate the drive units in response to detection of a predeterminable flow rate by the detection unit.

18. The delivery device of claim 4, wherein the actuation unit includes first and second drive units for actuating the first and second delivery units, and a trigger mechanism for actuating the first and second drive units in response to exhalation by the subject, and wherein the trigger mechanism is configured to actuate the drive units in response to generation of (i) a predeterminable pressure or (ii) a predeterminable flow rate.

19. The delivery device of claim 4, wherein the interface unit comprises a single integral unit.

20. The delivery device of claim 4, wherein the interface unit is packaged in protective packaging.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

How are People Using DrugPatentWatch?

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc