.

BioPharmaceutical Business Intelligence

  • Analyze global market entry opportunities
  • Identify first generic entrants
  • Uncover prior art in expired and abandoned patents

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Medtronic
Chinese Patent Office
Dow
Moodys
Express Scripts
Merck
Queensland Health
Colorcon
Teva
McKesson

Generated: November 24, 2017

DrugPatentWatch Database Preview

Claims for Patent: 8,022,082

« Back to Dashboard

Claims for Patent: 8,022,082

Title:Method for the administration of an anticholinergic by inhalation
Abstract: An inhalation kit comprising: (a) an inhaler displaying a flow resistance of about 0.01 to 0.1 {square root over (kPa)} min/L; and (b) an inhalable powder comprising tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 to 500 .mu.m, and a method of administering an inhalable powder containing tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 .mu.m to 500 .mu.m, the method comprising actuating an inhaler a flow resistance of about 0.01 to 0.1 {square root over (kPa)} min/L containing the inhalable powder.
Inventor(s): Zierenberg; Bernd (Bingen am Rhein, DE)
Assignee: Boehringer Ingelheim Pharma GmbH & Co., KG (Ingelheim am Rhein, DE)
Application Number:11/427,173
Patent Claims: 1. A method of administering an inhalable powder containing tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 .mu.m to 500 .mu.m, the method comprising actuating an inhaler with a flow resistance of about 0.01 to 0.1 {square root over (kPa)} min/L containing the inhalable powder, wherein the inhaler comprises: a housing containing two windows, a deck in which there are air inlet ports and which is provided with a screen secured by a screen housing, an inhalation chamber connected to the deck on which there is a push button provided with two sharpened pins and movable counter to a spring, a mouthpiece which is connected to the housing, the deck, and a cover via a spindle to enable it to be flipped open or shut, and three holes with diameters below 1 mm in the central region around the capsule chamber and underneath the screen housing and screen.

2. The method according to claim 1, wherein the amount of tiotropium in the inhalable powder is 0.001% to 5% of the inhalable powder.

3. The method according to claim 1, wherein the inhaler has a flow resistance of about 0.02 to 0.06 {square root over (kPa)} min/L.

4. The method according to claim 1, wherein the tiotropium is a chloride, bromide, iodide, methanesulfonate, p-toluenesulfonate, or methylsulfate salt.

5. The method according to claim 4, wherein the tiotropium is crystalline tiotropium bromide monohydrate.

6. An inhalation kit comprising: (a) an inhaler displaying a flow resistance of about 0.01 to 0.1 {square root over (kPa)} min/L; and (b) an inhalable powder comprising tiotropium in admixture with a physiologically acceptable excipient with an average particle size of between 10 to 500 .mu.m, wherein the inhaler comprises: a housing containing two windows, a deck in which there are air inlet ports and which is provided with a screen secured by a screen housing, an inhalation chamber connected to the deck on which there is a push button provided with two sharpened pins and movable counter to a spring, a mouthpiece which is connected to the housing, the deck, and a cover via a spindle to enable it to be flipped open or shut, and three holes with diameters below 1 mm in the central region around the capsule chamber and underneath the screen housing and screen.

7. The inhalation kit according to claim 6, wherein the amount of tiotropium in the inhalable powder is 0.001% to 5% of the inhalable powder.

8. The inhalation kit according to claim 7, wherein the tiotropium is a chloride, bromide, iodide, methanesulfonate, p-toluenesulfonate, or methylsulfate salt.

9. The inhalation kit according to claim 8, wherein the tiotropium is crystalline tiotropium bromide monohydrate.

10. The inhalation kit according to claim 6, wherein the flow resistance of the inhaler is about 0.02 to 0.06 {square root over (kPa)} min/L.

11. The inhalation kit according to claim 10, wherein the tiotropium is a chloride, bromide, iodide, methanesulfonate, p-toluenesulfonate, or methylsulfate salt.

12. The inhalation kit according to claim 11, wherein the tiotropium is crystalline tiotropium bromide monohydrate.

13. The inhalation kit according to claim 6, wherein the tiotropium is a chloride, bromide, iodide, methanesulfonate, p-toluenesulfonate, or methylsulfate salt.

14. The inhalation kit according to claim 13, wherein the tiotropium is crystalline tiotropium bromide monohydrate.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Serving leading biopharmaceutical companies globally:

Teva
UBS
Chinese Patent Office
Medtronic
Baxter
Covington
Johnson and Johnson
Accenture
McKesson
Novartis

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2017 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch:



Google
Twitter
Google Plus
botpot