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|Abstract:||The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.|
|Inventor(s):||Olhava; Edward J. (Newton, MA), Danca; Mihaela Diana (Mendham, NJ)|
|Assignee:||Millennium Pharmaceuticals, Inc. (Cambridge, MA)|
1. A compound of formula (I): ##STR00009## wherein: Z.sup.1 and Z.sup.2 together form a moiety derived from a boronic acid complexing agent.
2. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier.
3. A method of treating cancer, comprising administering to a patient in need of such treatment a pharmaceutical composition according to claim 2.
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