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McKesson
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Generated: November 17, 2017

DrugPatentWatch Database Preview

Claims for Patent: 8,003,681

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Claims for Patent: 8,003,681

Title:2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acet- ic acid and methyl ester
Abstract: A series of S-triazolyl .alpha.-mercaptoacetanilides having general structure (1) are provided, where Q is CO.sub.2H, CONR.sub.2, SO.sub.3H, or SO.sub.2NR.sub.2. The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections. ##STR00001##
Inventor(s): Girardet; Jean-Luc (San Diego, CA), Koh; Yung-Hyo (Irvine, CA)
Assignee: Ardea Biosciences, Inc. (San Diego, CA)
Application Number:12/633,638
Patent Claims: 1. A compound having the structure: ##STR00326##

2. A compound having the structure: ##STR00327##
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Serving leading biopharmaceutical companies globally:

Novartis
Harvard Business School
US Department of Justice
Chubb
Colorcon
Dow
Cerilliant
AstraZeneca
Federal Trade Commission
Express Scripts

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