Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||Use of Lck inhibitors for treatment of immunologic diseases|
|Abstract:||The invention relates to a method of treating immunologic diseases or pathological conditions involving an immunologic component using certain Lck inhibitors already known as kinase inhibitors for therapy in oncology, optionally in combination with one or more other drugs selected from NSAIDs, steroids, DMARDs, immunsuppressives, biologic response modifiers and antinfectives, pharmaceutical compositions comprising said Lck inhibitors together with said other drugs, and the use of the Lck inhibitors for the manufacture of a pharmaceutical composition for the treatment of immunologic diseases or pathological conditions involving an immunologic component.|
|Inventor(s):||Roth; Gerald Juergen (Biberach, DE), Heckel; Armin (Biberach, DE), Walter; Rainer (Biberach, DE), Hilberg; Frank (Vienna, AT), Hauptmann; Rudolf (Ebreichsdorf, AT), Stefanic; Martin Fredrich (Warthausen-Birkenhard, DE), Colbatzky; Florian (Stafflangen, DE), Ernest; Steffan (Moelnlycke, SE)|
|Assignee:||Boehringer Ingelheim Pharma GmbH & Co. KG (Ingelheim am Rhein, DE)|
1. A method for treating lung fibrosis comprising administering to a patient in need of such treatment an effective amount of a pharmaceutical composition comprising
(Z)-3-(1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)- -phenylamino)-1-phenyl-methylene)-6-methoxycarbonyl-2-indolinone or a tautomer, stereoisomer or physiologically acceptable salt thereof.
2. The method according to claim 1, wherein the pharmaceutical composition is administered orally, parenterally, or rectally.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.