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Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
Argus Health
Fish and Richardson
Harvard Business School

Generated: April 22, 2018

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Claims for Patent: 7,989,474

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Summary for Patent: 7,989,474
Title:Use of Lck inhibitors for treatment of immunologic diseases
Abstract: The invention relates to a method of treating immunologic diseases or pathological conditions involving an immunologic component using certain Lck inhibitors already known as kinase inhibitors for therapy in oncology, optionally in combination with one or more other drugs selected from NSAIDs, steroids, DMARDs, immunsuppressives, biologic response modifiers and antinfectives, pharmaceutical compositions comprising said Lck inhibitors together with said other drugs, and the use of the Lck inhibitors for the manufacture of a pharmaceutical composition for the treatment of immunologic diseases or pathological conditions involving an immunologic component.
Inventor(s): Roth; Gerald Juergen (Biberach, DE), Heckel; Armin (Biberach, DE), Walter; Rainer (Biberach, DE), Hilberg; Frank (Vienna, AT), Hauptmann; Rudolf (Ebreichsdorf, AT), Stefanic; Martin Fredrich (Warthausen-Birkenhard, DE), Colbatzky; Florian (Stafflangen, DE), Ernest; Steffan (Moelnlycke, SE)
Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG (Ingelheim am Rhein, DE)
Application Number:12/334,323
Patent Claims: 1. A method for treating lung fibrosis comprising administering to a patient in need of such treatment an effective amount of a pharmaceutical composition comprising (Z)-3-(1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)- -phenylamino)-1-phenyl-methylene)-6-methoxycarbonyl-2-indolinone or a tautomer, stereoisomer or physiologically acceptable salt thereof.

2. The method according to claim 1, wherein the pharmaceutical composition is administered orally, parenterally, or rectally.

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Serving hundreds of leading biopharmaceutical companies globally:

Johnson and Johnson
US Army

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