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Last Updated: September 21, 2021

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Claims for Patent: 7,919,625

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Summary for Patent: 7,919,625
Title:4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (CML)
Abstract: Compounds of the formula: ##STR00001## wherein: n is an integer from 1-3; X is N, CH, provided that when X is N, n is 2 or 3; R is alkyl of 1 to 3 carbon atoms; R.sup.1 is 2,4-diCl, 5-OMe; 2,4-diCl; 3,4,5-tri-OMe; 2-Cl, 5-OMe; 2-Me, 5-OMe; 2,4-di-Me; 2,4-diMe-5-OMe, 2,4-diCl, 5-OEt; R.sup.2 is alkyl of 1 to 2 carbon atoms, and pharmaceutically acceptable salts thereof.
Inventor(s): Boschelli; Frank (New City, NY), Golas; Jennifer M. (West Milford, NJ), Arndt; Kim T. (Towaco, NJ)
Assignee: Wyeth LLC (Madison, NJ)
Application Number:12/139,834
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,919,625
Patent Claims: 1. A pharmaceutical composition comprising a CML inhibiting amount of the compound 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl- -1-piperazinyl)propoxy]-3-quinolinecarbonitrile.

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