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Last Updated: March 18, 2024

Claims for Patent: 7,879,842


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Summary for Patent: 7,879,842
Title:Beta-crystalline form of ivabradine hydrochloride, a process for its preparation and pharmaceutical compositions containing it
Abstract: .beta.-Crystalline form of ivabradine of formula (I): ##STR00001## characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful as bradycardics.
Inventor(s): Horvath; Stephane (La Chapelle-Saint-Mesmin, FR), Auguste; Marie-Noelle (Orleans, FR), Damien; Gerard (Meung-sur-Loire, FR)
Assignee: Les Laboratoires Servier (Suresnes Cedex, FR)
Application Number:12/589,283
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,879,842
Patent Claims: 1. A .beta.-Crystalline form of ivabradine hydrochloride of formula (I): ##STR00003## having a powder X-ray diffraction diagram exhibiting peaks at 9.2, 18.4, 19.7, 21.6 and 25.3 deg 2 theta.

2. A .beta.-Crystalline form of ivabradine hydrochloride of formula (I): ##STR00004## having a powder X-ray diffraction diagram exhibiting peaks at 9.2, 9.7, 10.0 and 14.8 deg 2 theta.

3. A solid pharmaceutical composition comprising as active ingredient the .beta.-crystalline form of ivabradine hydrochloride of claim 1, in combination with one or more pharmaceutically acceptable, inert, non-toxic carriers.

4. A method for treating a condition selected from angina pectoris, myocardial infarct, and heart failure, such method comprising administering to a human, a therapeutically effective amount of the .beta.-crystalline form of ivabradine hydrochloride of claim 1.

5. A solid pharmaceutical composition comprising as active ingredient the .beta.-crystalline form of ivabradine hydrochloride of claim 2, in combination with one or more pharmaceutically acceptable, inert, non-toxic carriers.

6. A method for treating a condition selected from angina pectoris, myocardial infarct, and heart failure, such method comprising administering to a human, a therapeutically effective amount of the .beta.-crystalline form of ivabradine hydrochloride of claim 2.

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