Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
US Department of Justice
Johnson and Johnson
Cantor Fitzgerald
Farmers Insurance

Generated: June 24, 2018

DrugPatentWatch Database Preview

Claims for Patent: 7,820,694

« Back to Dashboard

Summary for Patent: 7,820,694
Title:Beta-2-adrenoreceptor agonists
Abstract: Compounds of formula ##STR00001## in free or salt or solvate form, where Ar is a group of formula ##STR00002## Y is carbon or nitrogen and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases.
Inventor(s): Cuenoud; Bernard (Horsham, GB), Bruce; Ian (Horsham, GB), Fairhurst; Robin A (Horsham, GB), Beattie; David (Horsham, GB)
Assignee: Novartis AG (Basel, CH)
Application Number:12/577,855
Patent Claims: 1. A combination comprising (a) (R)-5-[2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-1H-quin- olin-2-one in free or salt or solvate form; and (b) an anticholinergic or antimuscarinic agent.

2. A combination according to claim 1, in which (a) is (R)-5-[2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-1H-quin- olin-2-one maleate.

3. A combination according to claim 1, in which (b) is an anticholinergic or antimuscarinic agent selected from the group consisting of ipratropium bromide, oxitropium bromide and tiotropium bromide.

4. A combination according to claim 3, in which (b) is tiotropium bromide.

5. A pharmaceutical composition comprising a combination according to claim 1 and a pharmaceutically acceptable carrier.

6. A pharmaceutical composition according to claim 5, in which (a) is (R)-5-[2-(5,6-diethyl-indan-2-ylarnino)-1-hydroxy-ethyl]-8-hydroxy-1H-qui- nolin-2-one in free or salt or solvate form and in which (b) is, tiotropium bromide.

7. A method of treating a patient with an obstructive or inflammatory airways disease which comprises administering to the patient in need of such treatment a therapeutically effective amount of a combination according to claim 1.

8. A method of treating a patient according to claim 7, in which the disease is chronic obstructive pulmonary or airways disease.

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Cantor Fitzgerald
US Army
Chinese Patent Office
Johnson and Johnson
Daiichi Sankyo

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.