Claims for Patent: 7,812,049

Summary for Patent: 7,812,049

Title:	Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using .alpha..sub.1-adrenoceptor agonists
Abstract:	The present invention is directed to the treatment of skin erythema as exhibited in rosacea and other conditions characterized by increased erythema (redness) of the skin. These conditions exhibit dilation of blood vessels due to a cutaneous vascular hyper-reactivity. In particular, the present invention is directed to a novel composition and method for the treatment of skin erythema using .alpha..sub.1-adrenergic receptor (.alpha..sub.1-adrenoceptor) agonists incorporated into cosmetic, pharmacological or dermatological compositions for topical application to the skin.
Inventor(s):	Shanler; Stuart D. (New York, NY), Ondo; Andrew (Las Cruces, NM)
Assignee:	Vicept Therapeutics, Inc. (Malvern, PA)
Application Number:	10/763,807
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 7,812,049
Patent Claims:	1. A method of treating erythema resulting from rosacea in a subject comprising administering topically to the skin of said subject a composition comprising about 0.05% to about 30% of oxymetazoline as the sole active agent for treating the erythema resulting from rosacea, wherein said oxymetazoline is effective to decrease the erythema resulting from rosacea. 2. The method of claim 1, wherein said composition is selected from solutions, gels, lotions, creams, ointments, foams, emulsions, microemulsions, milks, serums, aerosols, sprays, dispersions, microcapsules, vesicles and microparticles thereof. 3. The method of claim 1, wherein said composition is selected from soaps and cleansing bars. 4. The method of claim 1, wherein said composition is a cream. 5. The method of claim 1, wherein said composition is a gel. 6. The method of claim 1, wherein said composition is a lotion. 7. The method of claim 1, wherein said erythema resulting from rosacea is elicited by at least one factor selected from the group consisting of intake of food, of hot or alcoholic drinks, temperature variations, heat, exposure to ultraviolet or infrared radiation, exposure to low relative humidity, exposure of the skin to strong winds or currents of air, exposure of the skin to surfactants, irritants, irritant dermatological topical agents, and cosmetics. 8. The method of claim 1, wherein said composition comprises about 0.1% to about 10% of said oxymetazoline. 9. The method of claim 1, wherein said composition further comprises about 50% to about 99.999% of a carrier. 10. The method of claim 1, wherein said composition further comprises about 70% to about 99.99% of a carrier.