Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

Daiichi Sankyo
US Department of Justice
Harvard Business School
Argus Health

Generated: April 23, 2018

DrugPatentWatch Database Preview

Claims for Patent: 7,786,133

« Back to Dashboard

Summary for Patent: 7,786,133
Title:Chemically modified small molecules
Abstract: The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer obtained from a monodisperse or bimodal water-soluble oligomer composition. A conjugate of the invention, when administered by any of a number of administration routes, exhibits a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the small molecule drug not attached to the water-soluble oligomer.
Inventor(s): Bentley; Michael D. (Huntsville, AL), Viegas; Tacey X. (Madison, AL), Goodin; Richard R. (Fayerville, TN), Cheng; Lin (Huntsville, AL), Zhao; Xuan (Huntsville, AL)
Assignee: Nektar Therapeutics (San Carlos, CA)
Application Number:11/015,196
Patent Claims: 1. 6-CH.sub.3--(OCH.sub.2CH.sub.2).sub.7--O-Naloxol or a pharmaceutically acceptable salt thereof.

2. .alpha.-6-CH.sub.3--(OCH.sub.2CH.sub.2).sub.7--O-Naloxol or a pharmaceutically acceptable salt thereof.

3. .beta.-6-CH.sub.3--(OCH.sub.2CH.sub.2).sub.7--O-Naloxol or a pharmaceutically acceptable salt thereof.

4. A pharmaceutical composition comprising the compound of any one of claims 1-3, or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
Queensland Health
Argus Health
Express Scripts

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.