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Last Updated: March 30, 2023

Claims for Patent: 7,741,338

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Summary for Patent: 7,741,338

Title:	Macrolides
Abstract:	The invention relates to the stabilization of poly-ene macrolides and to a particular macrolide obtained in crystalline form.
Inventor(s):	Navarro; Francois (Bruebach, FR), Petit; Samuel (Mont Saint-Aignan, FR), Stone; Guy (Crosshaven, IE)
Assignee:	Novartis AG (Basel, CH)
Application Number:	12/497,728
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 7,741,338
Patent Claims:	1. A solid mixture comprising 40-O-(2-hydroxy)ethyl-rapamycin and 2,6-di-tert-butyl-methylphenol (BHT). 2. A mixture according to claim 1, wherein said 2,6-di-tert-butyl-4-methylphenol (BHT) is present in a catalytic amount. 3. A pharmaceutical composition comprising the solid mixture of claim 1 together with one or more pharmaceutically acceptable diluent or carrier.

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Serving leading biopharmaceutical companies globally:

Merck

Mallinckrodt

Johnson and Johnson

McKinsey

Express Scripts

Boehringer Ingelheim

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