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Generated: August 21, 2018

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Claims for Patent: 7,700,645

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Summary for Patent: 7,700,645
Title:Pseudopolymorphic forms of a HIV protease inhibitor
Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sul- fonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
Inventor(s): Vermeersch; Hans Wim Pieter (Ghent, BE), Thone; Daniel Joseph Christiaan (Beerse, BE), Janssens; Luc Donne Marie-Louise (Malle, BE)
Assignee: Tibotec Pharmaceuticals Ltd. (Little Island, Co. Cork, IE)
Application Number:10/514,352
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,700,645
Patent Claims: 1. An ethanolate solvate of the compound (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sul- fonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate, in which the ratio of compound to ethanol is about 1:1.

2. A solvate having the formula: ##STR00002##

3. A composition comprising an ethanolate solvate of the compound (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sul- fonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate, in which the ratio of compound to ethanol is about 1:1, and an inert carrier.

4. The composition of claim 3 wherein the inert carrier is a pharmaceutically acceptable carrier.

5. The composition of claim 4 wherein the pharmaceutically acceptable carrier is a solid inert carrier.

6. A composition comprising a solvate having the formula: ##STR00003## and an inert carrier.

7. The composition of claim 6 wherein the inert carrier is a pharmaceutically acceptable earner.

8. The composition of claim 7 wherein the pharmaceutically acceptable carrier is a solid inert carrier.

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