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Claims for Patent: 7,687,662

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Claims for Patent: 7,687,662

Title:Proteasome inhibitors
Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
Inventor(s): Olhava; Edward J. (Newton, MA), Danca; Mihaela Diana (Mendham, NJ)
Assignee: Millennium Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:12/217,243
Patent Claims: 1. A compound of formula (I): ##STR00009## wherein: Z.sup.1 and Z.sup.2 together form a moiety derived from a boronic acid complexing agent; and Ring A is selected from the group consisting of ##STR00010##

2. The compound of claim 1, wherein Ring A is selected from the group consisting of ##STR00011##

3. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier.

4. A pharmaceutical composition comprising a compound of claim 2 and a pharmaceutically acceptable carrier.
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