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Claims for Patent: 7,625,582

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Claims for Patent: 7,625,582

Title:Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
Abstract:Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.
Inventor(s): Wong; Vernon G (Menlo Park, CA)
Assignee: Allergan, Inc. (Irvine, CA)
Application Number:11/738,409
Patent Claims: 1. A method for treating neovascularization in an eye of an individual, comprising: placing a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer in an eye of an individual, thereby treating neovascularization of the eye of the individual.

2. The method of claim 1, wherein the placing comprises placing the bioerodible drug delivery system in the vitreous of the eye.

3. The method of claim 1, wherein the bioerodible drug delivery system comprises dexamethasone.

4. The method of claim 1, wherein the bioerodible polymer comprises a polylactic acid polyglycolic acid (PLGA) copolymer.

5. The method of claim 1, wherein the bioerodible drug delivery system delivers the immunosuppressive agent for at least about 5 days.

6. The method of claim 1, wherein the bioerodible drug delivery system delivers the immunosuppressive agent for at least about 3 weeks.
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