BioPharmaceutical Business Intelligence

  • Analyze global market entry opportunities
  • Identify first generic entrants
  • Obtain formulation and manufacturing information
➤ Start Trial

or, See Plans & Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Baxter
McKinsey
Deloitte
UBS
Healthtrust
Mallinckrodt
QuintilesIMS
Farmers Insurance
Cantor Fitzgerald
Accenture

Generated: January 22, 2018

DrugPatentWatch Database Preview

Claims for Patent: 7,612,199

« Back to Dashboard

Summary for Patent: 7,612,199
Title:Polymorphic forms .alpha., .beta., and .gamma. of rifaximin
Abstract:Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin .alpha. and rifaximin .beta., and a poorly crystalline form named rifaximin .gamma., useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
Inventor(s): Viscomi; Guiseppe Glaudio (Bologna, IT), Campana; Manuela (Bologna, IT), Braga; Dario (Bologna, IT), Confortini; Donatella (Bologna, IT), Cannata; Vicenzo (Bologna, IT), Righi; Paolo (Bologna, IT), Rosini; Goffredo (Bologna, IT)
Assignee: Alfa Wassermann, S.p.A. (Bologna, IT)
Application Number:12/478,638
Patent Claims: 1. Rifaximin in polymorphic form .alpha., wherein the rifaximin has x-ray powder diffraction pattern peaks at about 7.4.degree.; 19.7.degree.; 21.0.degree. and 22.1.degree. 2-.theta. and wherein the rifaximin has a water content of less than 4.5%.

2. The compound of claim 1, wherein the rifaximin has a water content of between 2.0-3.0%.

3. The compound of claim 1, wherein the rifaximin has a water content of 2.5%.

4. Rifaximin in polymorphic form .beta., wherein the rifaximin has x-ray powder diffraction pattern peaks at about 5.4.degree.; 9.0.degree.; and 20.9.degree.2.theta. and wherein the rifaximin has a water content of greater than 5%.

5. The compound of claim 4, wherein the rifaximin has a water content of between 5.0-6.0%.

6. Rifaximin in polymorphic form .gamma., wherein the rifaximin has x-ray powder diffraction pattern peaks at about 5.0.degree., 7.1.degree., and 8.4.degree.2-.theta. and wherein the rifaximin has a water content of from between 0% to 2%.

7. The compound of claim 6, wherein the rifaximin has a water content of 1.5%.

For more information try a trial or see the plans and pricing

Serving leading biopharmaceutical companies globally:

AstraZeneca
Express Scripts
Queensland Health
Farmers Insurance
Citi
Federal Trade Commission
Deloitte
Colorcon
Argus Health

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

botpot