Manage your formulary budget
Find generic entry opportunities
Anticipate generic drug launch
Proactively manage your pharmacy inventory
Drug patents …
… from Kazakhstan to Kalamazoo
Deep knowledge on
small-molecule drugs and
the 110,000 global patents
Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||Heat stable colloidal iron oxides coated with reduced carbohydrates and uses thereof|
|Abstract:||Compositions, methods of making the compositions, and methods of using the compositions are provided for an enhanced magnetic resonance imaging agent and a hematinic agent, the agents comprising carboxyalkylated reduced polysaccharides coated ultrasmall superparamagnetic iron oxides. Methods of use of the carboxymethyl reduced dextran as a plasma extender are provided.|
|Inventor(s):||Groman; Ernest V. (Brookline, MA), Paul; Kenneth G. (Holliston, MA), Frigo; Timothy B. (Waltham, MA), Bengele; Howard (Canton, MA), Lewis; Jerome M. (Newton, MA)|
|Assignee:||AMAG Pharmaceuticals, Inc. (Cambridge, MA)|
1. A pharmaceutical composition in a vial comprising an injectable reduced carboxymethylated dextran iron oxide complex, wherein the carboxymethylated reduced dextran
comprises at least 750 micromole and less than 1500 micromole of carboxyl groups per gram of dextran and wherein said complex is stable at a temperature of at least about 100.degree. C.
2. A pharmaceutical composition in a vial according to claim 1, wherein the injectable complex is terminally sterilizable within the vial at a temperature of about 121.degree. C.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.