BioPharmaceutical Business Intelligence

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Serving leading biopharmaceutical companies globally:

Teva
Medtronic
McKesson
Colorcon
QuintilesIMS
Covington
Daiichi Sankyo
Express Scripts
UBS
Citi

Generated: January 18, 2018

DrugPatentWatch Database Preview

Claims for Patent: 7,456,207

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Summary for Patent: 7,456,207
Title:Vaginal pharmaceutical compositions and methods for preparing them
Abstract:Vaginal pharmaceutical compositions are described. These compositions contain (i) an active pharmaceutical ingredient selected from the group consisting of antimicrobial imidazoles and mixtures thereof, and (ii) a polysaccharide, wherein the pH of the composition is greater than 4.25 and less than about 8. In particularly preferred compositions, the active pharmaceutical ingredient includes metronidazole and the polysaccharide includes hypromellose. These compositions can be applied to vaginal tissue for treatment of various diseases, such as bacterial vaginosis, or for prophylaxis.
Inventor(s): Bentley; Christine Lynn (Caledonia, MI), Feldtmose; Karen (Pennsburg, PA)
Assignee: Teva Pharmaceuticals USA, Inc. (PA)
Application Number:10/946,133
Patent Claims: 1. A viscous vaginal pharmaceutical composition comprising an aqueous gel consisting essentially of: about 0.75% metronidazole; about 3.5% hypromellose; about 3% propylene glycol; about 0.05% edetate disodium; and about 0.08% methylparaben; about 0.02% propylparaben; and about 93% water, wherein the pH of the composition is from about 5 to about 6.5.

2. A vaginal insert comprising the composition of claim 1 housed in a medical device having a means for controlling the dose of the active pharmaceutical ingredient to a patient.

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Serving leading biopharmaceutical companies globally:

Julphar
Deloitte
AstraZeneca
Chinese Patent Office
Moodys
Novartis
Colorcon
Johnson and Johnson
Boehringer Ingelheim

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