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Serving hundreds of leading biopharmaceutical companies globally:

Citi
Express Scripts
Queensland Health
Merck
Julphar
McKinsey
Covington
Mallinckrodt
Federal Trade Commission

Generated: April 19, 2018

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Claims for Patent: 7,157,584

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Summary for Patent: 7,157,584
Title:Benzimidazole derivative and use thereof
Abstract:The present invention relates to a compound represented by the formula (I) ##STR00001## wherein R.sup.1 is a group represented by the formula ##STR00002## wherein R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7 and R.sup.8 are each independently a hydrogen atom or a C.sub.1-6 alkyl, or a salt thereof. The compound of the present invention is useful as an agent for the prophylaxis or treatment of circulatory diseases such as hypertension and the like and metabolic diseases such as diabetes and the like.
Inventor(s): Kuroita; Takanobu (Katano, JP), Sakamoto; Hiroki (Amagasaki, JP), Ojima; Mami (Amagasaki, JP)
Assignee: Takeda Pharmaceutical Company Limited (Osaka, JP)
Application Number:11/031,057
Patent Claims: 1. (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]met- hyl}-1H-benzimidazole-7-carboxylate or a pharmaceutically acceptable salt thereof.

2. (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]met- hyl}-1H-benzimidazole-7-carboxylate potassium salt.

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Serving hundreds of leading biopharmaceutical companies globally:

US Army
UBS
Teva
Boehringer Ingelheim
Queensland Health
Cipla
Accenture
McKinsey
Merck

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