|Title:||Corticosteroid-containing pharmaceutical composition|
|Abstract:||A foamable pharmaceutical composition comprising a corticosteroid, a quick-break foaming agent, a propellant and a buffering agent, sufficient to buffer the composition to within the range of pH 3.0 to 6.0 is disclosed. The quick-break foaming agent typically comprises an aliphatic alcohol, water, a fatty alcohol and a surface active agent. Due to the nature of the compositions of the invention, they are especially well-suited for use in the treatment of various skin diseases, and in particular, in the treatment of scalp psoriasis.|
|Inventor(s):|| Jones; Julie Irene (Harpenden, GB), Baker; Anthony Richard (West Horsley, GB), Halls; Neil Graham (Glen Waverley, AU), Watmough; Peter (Grimsby, GB), Marriott; Peter (Grimsby, GB) |
|Assignee:|| Connetics Australia Pty Ltd (Rowville, AU) |
1. A foamable pharmaceutical composition adapted for topical administration having the following composition: TABLE-US-00003 % w/w Betamethasone Valerate 0.120 Cetyl Alcohol BP 1.100
Octadecan-1-ol BP 0.500 Polysorbate 60 BP 0.400 Ethanol 57.790 Purified Water 33.690 Propylene Glycol BP 2.000 Citric Acid Anhydrous BP 0.073 Potassium Citrate 0.027 Butane/Propane 4.300 100.000.