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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
Healthtrust
AstraZeneca
Merck
Accenture
Queensland Health
Cantor Fitzgerald
UBS
Julphar

Generated: April 25, 2018

DrugPatentWatch Database Preview

Claims for Patent: 7,053,092

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Summary for Patent: 7,053,092
Title:5-HT1a receptor subtype agonist
Abstract: The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT.sub.1A receptor subtype, comprising as an active ingredient a carbostyril derivative or a salt thereof represented by the formula (1): ##STR00001## wherein the carbon-carbon bond between 3- and 4-positions in the carbostyril skeleton is a single or a double bond.
Inventor(s): Jordon; Shaun (Germantown, MD), Kikuchi; Tetsuro (Tokushima, JP), Tottori; Katsura (Kamiita-cho, JP), Hirose; Tsuyoshi (Tokushima, JP), Uwahodo; Yasufumi (Tokushima, JP)
Assignee: Otsuka Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:10/055,915
Patent Claims: 1. A method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT.sub.1A receptor subtype wherein the disorder is depression selected from the group consisting of endogenous depression, major depression, melancholia and treatment resistant depression, which comprises administering to said patient a therapeutically effective amount of a carbostyril compound of formula (1), or a pharmaceutically acceptable salt or solvate thereof, wherein said patient is a mammal: ##STR00003## wherein the carbon-carbon bond between 3- and 4- positions in the carbostyril skeleton is a single or a double bond.

2. The method of claim 1 wherein the carbostyril compound is 7-{4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxyl}-3,4-dihydrocarbostyri- l.

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Serving hundreds of leading biopharmaceutical companies globally:

UBS
Deloitte
Julphar
Colorcon
Mallinckrodt
Cipla
Federal Trade Commission
Merck
McKinsey

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