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Claims for Patent: 6,982,096

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Claims for Patent: 6,982,096

Title:Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol
Abstract:The invention relates to the use of arsenic compounds to treat a variety of leukemia, lymphoma and solid tumors. Further, the arsenic compounds may be used in combination with other therapeutic agents, such as a retinoid. The invention also provides a process for producing arsenic trioxide formulations.
Inventor(s): Warrell, Jr.; Raymond P. (Westfield, NJ), Pandolfi; Pier Paolo (New York, NY), Gabrilove; Janice L. (New York, NY)
Assignee: Memorial Sloan-Kettering Cancer Center (New York, NY)
Application Number:10/759,290
Patent Claims: 1. A method for treating cancer, comprising determining the weight of a patient diagnosed with cancer, determining a therapeutically effective dosage amount of arsenic trioxide based upon said weight of said patient, and administering said therapeutically effective dosage amount to said patient.

2. The method of claim 1, wherein said cancer is a hematological cancer.

3. The method of claim 1, wherein said cancer is a leukemia.

4. A method for determining a dose of arsenic trioxide to treat cancer, comprising determining the weight of a patient diagnosed with cancer and determining a therapeutically effective dosage amount of said arsenic trioxide based upon said weight of said patient.

5. The method of claim 4, wherein said cancer is a hematological cancer.

6. The method of claim 4, wherein said cancer is a leukemia.
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