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Claims for Patent: 6,960,577

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Claims for Patent: 6,960,577

Title: Combination therapy for treatment of refractory depression
Abstract:Methods for treating a patient suffering from or susceptible to treatment resistant major depression comprising administering olanzapine and fluoxetine are disclosed.
Inventor(s): Tollefson; Gary Dennis (Indianapolis, IN)
Assignee: Eli Lilly and Company (Indianapolis, IN)
Application Number:10/144,159
Patent Claims: 1. A method for treating a patient suffering from or susceptible to treatment resistant major depression, comprising administering to said patient an effective amount of a first component which is olanzapine or a pharmaceutically acceptable salt thereof, in combination with an effective amount of a second component which is fluoxetine, or a phannaceutically acceptable salt thereof.

2. A method according to claim 1 where the administration of the compounds is oral.

3. A method for treating a patient suffering from or susceptible to treatment resistant major depression, comprising administering to said patient an effective amount of a first component which is olanzapine, in combination with an effective amount of a second component which is fluoxetine.

4. A method for treating a patient suffering from or susceptible to treatment resistant major depression, comprising administering to said patient an effective amount of a first component which is olanzapine in combination with an effective amount of a second component which is fluoxetine hydrochloride.
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