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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Julphar
Queensland Health
Boehringer Ingelheim
AstraZeneca
Mallinckrodt
US Army
Argus Health
Covington
McKinsey

Generated: October 17, 2017

DrugPatentWatch Database Preview

Claims for Patent: 6,875,872

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Claims for Patent: 6,875,872

Title: Compounds
Abstract:The novel optically pure compounds Na.sup.+, Mg.sup.2+, Li.sup.+, K.sup.+, Ca.sup.2+ and N.sup.+ (R).sub.4 salts of (+)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H- benzimidazole or (-)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H- benzimidazole, in particular sodium and magnesium salt form thereof, where R is an alkyl with 1-4 carbon atoms, processes for the preparation thereof and pharmaceutical preparations containing the compounds as active ingredients, as well as the use of the compounds in pharmaceutical preparations and intermediates obtained by preparing the compounds.
Inventor(s): Lindberg; Per Lennart (Molndal, SE), Von Unge; Sverker (Fjaras, SE)
Assignee: AstraZeneca (Sodertalje, SE)
Application Number:09/690,044
Patent Claims: 1. Magnesium salt of (-)-5-methoxy-2-[[(4-methoxy-3,5,dimethyl-2-pyridinyl)methyl]sulfinyl]-1H- benzimidazole in an optical purity of at least about 94% enantiomeric excess.

2. The compound according to claim 1, when the optical purity is at least 94% enantiomeric excess.

3. The compound according to claim 1 or 2, wherein the compound is in crystaline form.

4. Magnesium salt of (-)-5-methoxy-2-[[(4-methoxy-3,5,dimethyl-2-pyridinyl)methyl]-sulfinyl]-1H -benzimidazole in an optical purity of at least about 98.4% enantiomeric excess.

5. The compound according to claim 4, wherein the optical purity is at least 98.4% enantiomeric excess.

6. The compound according to claim 4 or 5, wherein the compound is in crystaline form.

7. Magnesium salt of (-)-5-methoxy-2-[[(4-methoxy-3,5,dimethyl-2-pyridinyl)methyl]-sulfinyl]-1H -benzimidazole in an optical purity of at last about 99.8% enantiomeric excess.

8. The compound according to claim 7, wherein the optical purity is at least 99.8% enantiomeric excess.

9. The compound according to claim 7 or 8, wherein the compound is in crystalline form.

10. Magnesium salt of (-).sub.5 -methoxy-2-[[(4-methoxy-3,5,dimethyl-2-pyridinyl)methyl]-sulfinyl]-1H-benz imidazole in an optical purity of at least about 99.9% enantiomeric excess.

11. The compound according to claim 10, wherein the optical purity is at least 99.9% enantiomeric excess.

12. The compound according to claim 10, wherein the compound is in crystalline form.
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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Dow
Teva
Novartis
Farmers Insurance
Julphar
Healthtrust
Express Scripts
Federal Trade Commission
Fish and Richardson

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