Generated: May 26, 2017
|Title:||Oligopeptide lyophilisate, their preparation and use|
|Abstract:||A novel lyophilizate and method of preparation as well as the use of the lyophilizate to treat female infertility and for gonad protection. Cetrorelix is dissolved in acetic acid 30% v/v, the solution is transferred to water and freeze dried.|
|Inventor(s):||Engel; Jurgen (Alzenau, DE), Wichert; Burkhard (Bielefeld, DE), Sauerbier; Dieter (Werter, DE), Reissmann; Thomas (Frankfurt am Main, DE)|
|Assignee:||Zentaris AG (Frankfurt, DE)|
1. A method of treating female infertility which comprises administering, to a female undergoing controlled ovarian stimulation, an effective amount of pharmaceutical
composition comprising a lyophilizate of a certrorelix solution containing 100-10,000 parts by weight of acetic acid per part of dissolved cetrorelix, thereby preventing premature ovulation.
2. The method according to claim 1, wherein the lyophilizate further comprises a bulking agent.
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