.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 6,677,326

« Back to Dashboard

Claims for Patent: 6,677,326

Title: Corticosteroid formulation comprising less than 2.5 mg prednisolone for once daily administration
Abstract:The subject invention concerns a unit dose formulation comprising less than 2.5 mg of prednisolone or an equivalent, equipotent amount of another corticosteroid. One embodiment of a method of the invention concerns once daily administration of the unit dose formulation between midnight and 6 a.m. for the treatment of rheumatoid arthritis.
Inventor(s): Bardsley; Hazel Judith (Cambridge, GB), Bannister; Robin Mark (Essex, GB), Gilbert; Julian Clive (Essex, GB)
Assignee: Arakis, Ltd. (GB)
Application Number:10/263,044
Patent Claims: 1. A unit dose formulation comprising less than 2.5 mg of prednisolone or an equivalent, equipotent amount of another corticosteroid.

2. The formulation according to claim 1, which comprises at least 0.25 mg of prednisolone or said equivalent.

3. The formulation according to claim 2, which comprises 0.5 to 2 mg of prednisolone or said equivalent.

4. The formulation according to claim 3, which comprises 1 to 1.25 mg of prednisolone or said equivalent.

5. The formulation according to claim 1, adapted to release at least 90% by weight of prednisolone or said equivalent 2 to 8 hours after administration.

6. The formulation according to claim 1, wherein said corticosteroid is a glucocorticoid.

7. The formulation according to claim 1, wherein said corticosteroid is selected from the group consisting of prednisone, budesonide, methylprednisolone, fluticasone, betamethasone, and deflazacort.

8. The formulation according to claim 7, wherein said corticosteroid is prednisone.

9. A method for the treatment of a patient suffering from a condition selected from the group consisting of asthma, inflammatory bowel disease, psoriasis, psoriatic arthritis, polymyalgia rheumatica, chronic obstructive pulmonary disease, and rheumatoid arthritis and other polyarthropathies, which comprises administering to the patient a unit dosage formulation comprising less than 2.5 mg of prednisolone or an equivalent, equipotent amount of another corticosteroid.

10. The method according to claim 9, wherein the formulation comprises at least 0.25 mg of prednisolone or said equivalent.

11. The method according to claim 10, wherein the formulation comprises 0.5 to 2 mg of the prednisolone or said equivalent.

12. The method according to claim 11, wherein the formulation comprises 1 to 1.25 mg of the prednisolone or said equivalent.

13. The method according to claim 9, wherein the formulation is adapted to release at least 90% by weight of the prednisolone or said equivalent 2 to 8 hours after administration.

14. The method according to claim 9, wherein said corticosteroid is a glucocorticoid.

15. The method according to claim 9, wherein said corticosteroid is selected from the group consisting of prednisone, budesonide, methylprednisolone, flutacasone, betamethasone, and deflazacort.

16. The method according to claim 15, wherein said corticosteroid is prednisone.

17. The method according to claim 8, wherein said corticosteroid is administered between midnight and 6 a.m.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

How are People Using DrugPatentWatch?

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc