.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 6,534,070

« Back to Dashboard

Claims for Patent: 6,534,070

Title: Composition with azelaic acid
Abstract:The invention relates to a pharmaceutical composition having the following constituents: azelaic acid, polyacrylic acid, triacylglyceride, propylene glycol, polysorbate, soya lecithin, water and salts. The composition is a hydrogel which is suited for the treatment of rosacea, presbyderma, melasma or skin irritations.
Inventor(s): Franke; Patrick (Berlin, DE), Gunther; Clemens (Berlin, DE), Riedl; Jutta (Inzlingen, DE)
Assignee: Schering Aktiengesellschaft (Berlin, DE)
Application Number:09/554,738
Patent Claims: 1. A composition that comprises: (i) azelaic acid as a therapeutically active ingredient in a concentration of 5 to 20% by weight, (iii) at least one triacylglyceride in a concentration of 0.5 to 5% by weight, (iv) propylene glycol, and (v) at least one polysorbate, in an aqueous phase that further comprises water and salts, and the composition further comprises (ii) at least one polyacrylic acid, and (vi) lecithin, wherein the composition is in the form of a hydrogel.

2. A composition according to claim 1, wherein the composition is in a form for topical administration.

3. A composition according to claim 1, wherein the lecithin is soybean lecithin.

4. A composition according to claim 1, wherein the lecithin is present at a concentration within the range of greater than 0% to 1% by weight.

5. A composition according to claim 1, wherein the individual components, independently of one another, have the following concentrations; (ii) at least one polyacrylic acid at a concentration of 0.5 to 2% by weight, (iii) at least one triacylglyceride at a concentration of 0.5 to 5% by weight, (iv) propylene glycol at a concentration of 5 to 15% by weight, and (v) at least one polysorbate at a concentration of 0.5 to 3% by weight.

6. A composition according to claim 1, wherein the individual components, independently of one another, have the following concentrations: (ii) at least one polyacrylic acid at a concentration of 1.+-.0.25% by weight, (iii) at least one triacylglyceride at a concentration of 2.+-.1% by weight, (iv) propylene glycol at a concentration of 10.+-.2-% by weight, and (v) at least one polysorbate at a concentration of 2.+-.0.5% by weight.

7. A composition according to claim 1, wherein the composition further comprises at least one physiologically compatible, pharmacological adjuvant or vehicle.

8. A method for treating rosacea, presbyderma, melasma, acne and/or skin irritations in a patient, comprising administering to the patient in need thereof a therapeutically effective amount of the composition according to claim 1.

9. The method of claim 8, wherein the composition is administered topically.

10. A composition according to claim 1, wherein the azelaic acid is present at a concentration of 10 to 18% by weight.

11. A composition according to claim 1, wherein the lecithin is present at a concentration within the range of greater than 0% to 3% by weight.

12. A composition according to claim 1, further comprising benzoic acid.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

How are People Using DrugPatentWatch?

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc