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Moodys
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Federal Trade Commission
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QuintilesIMS
Chubb
Queensland Health
Baxter
Fish and Richardson

Generated: April 20, 2018

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Claims for Patent: 6,444,859

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Summary for Patent: 6,444,859
Title: Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid
Abstract:The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
Inventor(s): Bieniarz; Christopher (Highland Park, IL), Chang; Steve H. (Gurnee, IL), Cromack; Keith R. (Lake Bluff, IL), Huang; Shuyen L. (Riverwoods, IL), Kawai; Toshikazu (Saitama, JP), Kobayashi; Manami (Saitama, JP), Loffredo; David (Elmnurst, IL), Raghavan; Rajagopalan (Grayslake, IL), Speicher; Earl R. (Buffalo Grove, IL), Stelmach; Honorate A. (Lake Forest, IL)
Assignee: Abbott Laboratories (Abbott Park, IL) Central Glass Company LTD (Tokyo, JP)
Application Number:09/924,573
Patent Claims: 1. A method for preventing degradation by Lewis acids of a quantity of sevoflurane, said method comprising providing a quantity of sevoflurane and contacting said quantity of sevoflurane with an amount of Lewis acid inhibitor, said amount of Lewis acid inhibitor being selected such that said Lewis acid inhibitor is present in an amount of at least 150 parts per million parts of a total of said quantity of sevoflurane and said amount of Lewis acid inhibitor.

2. A method in accordance with claim 1, wherein said Lewis acid inhibitor is selected from a group consisting of water, butylated hydroxytoluene, methylparaben, propylparaben, propofol, and thymol.

3. A method in accordance with claim 1, wherein said Lewis acid inhibitor is water.

4. A sevoflurane product protected from degradation by Lewis acids in accordance with the method of claim 1.

5. A sevoflurane product protected from degradation by Lewis acids in accordance with the method of claim 2.

6. A sevoflurane product protected from degradation by Lewis acids in accordance with the method of claim 3.

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Serving hundreds of leading biopharmaceutical companies globally:

Accenture
Johnson and Johnson
Mallinckrodt
Harvard Business School
Cerilliant
Merck
Healthtrust
Daiichi Sankyo
Chinese Patent Office

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