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Claims for Patent: 6,358,986

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Claims for Patent: 6,358,986

Title: Polymorphs of telmisartan
Abstract:The invention relates to polymorphs of 4'-[2-n-propyl-4-methyl-6-(1-methylbenzimid-azol-2-yl)benzimidazol-1-ylmet hyl]biphenyl-2-carboxylic acid (INN: telmisartan), particularly polymorphic form B, mixtures of the polymorphs, processes for preparing telmisartan containing form B and the use thereof for preparing a pharmaceutical composition.
Inventor(s): Schneider; Heinrich (late of Ingelheim, DE)
Assignee: Boehringer Ingelheim Pharma KG (Ingelheim, DE)
Application Number:09/480,211
Patent Claims: 1. A mixture of two polymorphic crystalline forms of Telmisartan (the compound of formula I) ##STR3##

wherein the first polymorphic crystalline form, designated form A, has an endothermic maximum at 269.+-.2.degree. C. which occurs during thermal analysis using DSC, and wherein the second polymorphic crystalline form, designated form B, has endothermic maxima at 183.+-.2.degree. C. and at 269.+-.2.degree. C which occur during thermal analysis using DSC, and wherein the ratio of form A to form B in said mixture is in the range from 10:90 to 60:40.

2. A pharmaceutical composition comprising the mixture of forms A and B of telmisartan, in accordance with claim 1, and a pharmaceutically acceptable carrier.
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