Manage your formulary budget
Proactively manage your pharmacy inventory
Find generic entry opportunities
Deep knowledge on
small-molecule drugs and
the 110,000 global patents
Anticipate generic drug launch
Drug patents …
… from Kazakhstan to Kalamazoo
Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||Polymorphs of telmisartan|
|Abstract:||The invention relates to polymorphs of 4'-[2-n-propyl-4-methyl-6-(1-methylbenzimid-azol-2-yl)benzimidazol-1-ylmet hyl]biphenyl-2-carboxylic acid (INN: telmisartan), particularly polymorphic form B, mixtures of the polymorphs, processes for preparing telmisartan containing form B and the use thereof for preparing a pharmaceutical composition.|
|Inventor(s):||Schneider; Heinrich (late of Ingelheim, DE)|
|Assignee:||Boehringer Ingelheim Pharma KG (Ingelheim, DE)|
1. A mixture of two polymorphic crystalline forms of Telmisartan (the compound of formula I) ##STR3##
wherein the first polymorphic crystalline form, designated form A, has an endothermic maximum at 269.+-.2.degree. C. which occurs during thermal analysis using DSC, and wherein the second polymorphic crystalline form, designated form B, has endothermic maxima at 183.+-.2.degree. C. and at 269.+-.2.degree. C which occur during thermal analysis using DSC, and wherein the ratio of form A to form B in said mixture is in the range from 10:90 to 60:40.
2. A pharmaceutical composition comprising the mixture of forms A and B of telmisartan, in accordance with claim 1, and a pharmaceutically acceptable carrier.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.