|Title:||Phenidate drug formulations having diminished abuse potential|
|Abstract:||Phenidate drug formulations are provided having reduced potential for drug abuse. Dosage forms for treating Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder, AIDS Dementia Complex and cognitive decline in HIV-AIDS are provided which minimize drug hypersensitivity, toxicity, side effects, euphoric effect, and drug abuse potential. Such dosage forms comprise D-threo stereoisomer of a phenidate in the substantial absence of all other stereoisomers.|
|Inventor(s):||Zeitlin; Andrew L. (Millington, NJ), Dariani; Maghsoud M. (Fanwood, NJ)|
|Assignee:||Celgene Corporation (Warren, NJ)|
1. A pharmaceutical unit dosage comprising from about 1 to about 50 milligrams of D-threo-methylphenidate or a pharmaceutically acceptable salt thereof said dosage having less
than 10% by weight of other stereoisomers of methylphenidate or the salt thereof.
2. The unit dosage of claim 1 comprising from about 2 to about 20 milligrams of D-threo-methylphenidate.
3. The unit dosage of claim 1 comprising from about 21/2 to about 12 milligrams of D-threo-methylphenidate.
4. The unit dosage of claim 1 in a form suitable for oral administration.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.