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Last Updated: September 18, 2020

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Claims for Patent: 6,221,392

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Summary for Patent: 6,221,392
Title: Rapidly dissolving robust dosage form
Abstract:The invention is directed to a hard tablet that can be stored, packaged and processed in bulk. Yet the tablet dissolves rapidly in the mouth of the patient with a minimum of grit. The tablet is created from an active ingredient mixed into a matrix of a nondirect compression filler and a relatively high lubricant content.
Inventor(s): Khankari; Rajendra K. (Maple Grove, MN), Hontz; John (Plymouth, MN), Chastain; Sara J. (Maple Grove, MN), Katzner; Leo (Eden Prairie, MN)
Assignee: Cima Labs Inc. (Eden Prairie, MN)
Application Number:09/464,882
Patent Claims: 1. A hard, compressed, rapidly dissolvable dosage form adapted for direct oral dosing comprising: an active ingredient and a matrix including a nondirect compression filler and a lubricant, said dosage form being adapted to rapidly dissolve in the mouth of a patient and thereby liberate said active ingredient, and having a friability of about 2% or less when tested according to the U.S.P.

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Serving leading biopharmaceutical companies globally:

McKinsey
Moodys
Merck
Boehringer Ingelheim
AstraZeneca
Baxter

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