|Title:|| Rapidly dissolving robust dosage form|
|Abstract:||The invention is directed to a hard tablet that can be stored, packaged and processed in bulk. Yet the tablet dissolves rapidly in the mouth of the patient with a minimum of grit. The tablet is created from an active ingredient mixed into a matrix of a nondirect compression filler and a relatively high lubricant content.|
|Inventor(s):|| Khankari; Rajendra K. (Maple Grove, MN), Hontz; John (Plymouth, MN), Chastain; Sara J. (Maple Grove, MN), Katzner; Leo (Eden Prairie, MN) |
|Assignee:|| Cima Labs Inc. (Eden Prairie, MN) |
1. A hard, compressed, rapidly dissolvable dosage form adapted for direct oral dosing comprising: an active ingredient and a matrix including a nondirect compression filler and a
lubricant, said dosage form being adapted to rapidly dissolve in the mouth of a patient and thereby liberate said active ingredient, and having a friability of about 2% or less when tested according to the U.S.P.