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Claims for Patent: 6,153,635

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Claims for Patent: 6,153,635

Title: Methods and kits for treating vulvovaginal candidiasis with miconazole nitrate
Abstract:A method for treating vulvovaginal candidiasis including the steps of: (a) administering a single dose of an effective amount of miconazole nitrate in a pharmaceutically acceptable carrier intra-vaginally; and (b) applying miconazole nitrate in a pharmaceutically acceptable carrier to the vulva. Also a kit for the treatment of vulvovaginal candidiasis including: (a) a single dose of an effective amount of miconazole nitrate in a pharmaceutically acceptable carrier and in a form adapted to be administered intra-vaginally; and (b) an amount of miconazole nitrate in a pharmaceutically acceptable carrier adapted to be applied topically to the vulva.
Inventor(s): Upmalis; David H. (Newtown, PA)
Assignee:
Application Number:09/197,019
Patent Claims: 1. A method for treating vulvovaginal candidiasis consisting essentially of the steps of:

(a) administering a single dose of an effective amount of miconazole nitrate in a pharmaceutically acceptable carrier intra-vaginally; and

(b) applying topically miconazole nitrate in a pharmaceutically acceptable carrier to the vulva.

2. The method of claim 1, wherein the single dose of miconazole nitrate administered intra-vaginally comprises about 400 to about 2000 mg of miconazole nitrate.

3. The method of claim 1, wherein the single dose of miconazole nitrate administered intra-vaginally comprises about 600 to about 1200 mg of miconazole nitrate.

4. The method of claim 1, wherein the single dose of miconazole nitrate administered intra-vaginally comprises 2.5 g of 16% miconazole nitrate cream, 5 g of 8% miconazole nitrate cream, 5 g 12% miconazole nitrate cream or 5 g 16% miconazole nitrate cream.

5. The method of claim 1, wherein step (b) is performed 1-2 times per day.

6. The method of claim 1, wherein step (b) is performed 1-2 times per day for about 7 days.

7. The method of claim 3, wherein step (b) is performed 1-2 times per day for about 7 days.

8. A kit for the treatment of vulvovaginal candidiasis consisting essentially of:

(a) a single dose of an effective amount of miconazole nitrate in a pharmaceutically acceptable carrier and in a form adapted to be administered intra-vaginally; and

(b) an amount of miconazole nitrate in a pharmaceutically acceptable carrier adapted to be applied topically to the vulva.

9. The kit of claim 8, wherein the single dose of miconazole nitrate adapted to be administered intra-vaginally comprises about 400 to about 2000 mg of miconazole nitrate.

10. The kit of claim 8, wherein the single dose of miconazole nitrate adapted to be administered intra-vaginally comprises about 600 to about 1200 mg of miconazole nitrate.

11. The kit of claim 8, wherein the single dose of miconazole nitrate adapted to be administered intra-vaginally comprises 2.5 g of 16% miconazole nitrate cream, 5 g of 8% miconazole nitrate cream, 5 g 12% miconazole nitrate cream or 5 g 16% miconazole nitrate cream.

12. The kit of claim 8, wherein the amount of miconazole nitrate in a pharmaceutically acceptable carrier adapted to be applied topically to the vulva is a sufficient amount to be applied 1-2 times per day for about 7 days.

13. The kit of claim 10, wherein the amount of miconazole nitrate in a pharmaceutically acceptable carrier adapted to be applied topically to the vulva is a sufficient amount to be applied 1-2 times per day for about 7 days.
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