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Claims for Patent: 6,143,769

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Claims for Patent: 6,143,769

Title: Phenylacetic acid benzylamides
Abstract:The present application relates to the uses of phenylacetic acid benzylamides and new (S)(+)-2-ethoxy-4-[N-[1-2-piperidino-phenyl)-3-methyl-1-butyl]-aminocarbon ylmethyl]-benzoic acid and the salts thereof, which have valuable pharmacological properties, namely an effect on the intermediate metabolism, but particularly the effect of lowering blood sugar.
Inventor(s): Grell; Wolfgang (Biberach, DE), Hurnaus; Rudolf (Biberach, DE), Griss, deceased; Gerhart (late of Biberach, DE), Sauter; Robert (Laupheim, DE), Reiffen; Manfred (Biberach, DE), Rupprecht; Eckhard (Aulendorf-Tannhausen, DE)
Assignee: Karl Thomae GmbH (Biberach an der Riss, DE)
Application Number:08/180,587
Patent Claims: 1. Substantially optically pure (S)(+)-2-ethoxy-4[N-{1-(2-piperidino-phenyl)-3-methyl-1-butyl]aminocarbony lmethyl]-benzoic acid and the salts thereof with inorganic or organic acids or bases.

2. The compound according to claim 1 having an optical purity of at least ee=95%.

3. The compound according to claim 1 having an optical purity of at least ee=98%.

4. The physiologically acceptable salts of the compound according to claim 1 with organic or inorganic acids or bases.

5. A pharmaceutical composition comprising a compound according to claim 1 and one or more inert carriers or diluents.

6. A method for treating diabetes mellitus comprising administering a therapeutically effective amount of the compound as recited in claim 1.
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