DrugPatentWatch Database Preview
« Back to Dashboard
Summary for Patent: 6,143,326
|Title:||Oral pharmaceutical preparation containing ibandronat|
|Abstract:||The invention is directed to well-tolerated pharmaceutical compositions for oral application, containing ibandronate or a physiologically tolerable salt thereof as active substance, the administration form consisting of an active substance-containing inner portion enclosed in such fashion by a coat free of active substance that rapid release of the active substance takes place.|
|Inventor(s):||Mockel; Jorn (Heidelberg, DE), Gabel; Rolf-Dieter (Schwetzingen, DE), Woog; Heinrich (Laudenbach, DE)|
|Assignee:||Roche Diagnostics GmbH (Mannheim, DE)|
1. A method of treating a bone disease in a patient in need thereof, comprising orally administering to the patient a pharmaceutical formulation comprising a tablet core
containing about 0.1 to 100 mg of ibandronate and a coating which is free of ibandronate and has the following proportional composition:
(a) about 51.425% by weight of methylhydroxypropylcellulose;
(b) about 24.650% by weight of titanium dioxide;
(c) about 15.000% by weight of polyethylene glycol; and
(d) about 8.925% by weight of talc.
2. The method of claim 1, wherein the bone disease is related to a disorder in calcium metabolism.
3. The method of claim 1, wherein the bone disease is selected from the group consisting of hypercalcemia, osteoporosis, tumor osteolysis, and Paget's disease.
For more information try a trial or see the plans and pricing
Serving hundreds of leading biopharmaceutical companies globally: