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US Department of Justice
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Daiichi Sankyo

Generated: May 21, 2018

DrugPatentWatch Database Preview

Claims for Patent: 6,143,326

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Summary for Patent: 6,143,326
Title: Oral pharmaceutical preparation containing ibandronat
Abstract:The invention is directed to well-tolerated pharmaceutical compositions for oral application, containing ibandronate or a physiologically tolerable salt thereof as active substance, the administration form consisting of an active substance-containing inner portion enclosed in such fashion by a coat free of active substance that rapid release of the active substance takes place.
Inventor(s): Mockel; Jorn (Heidelberg, DE), Gabel; Rolf-Dieter (Schwetzingen, DE), Woog; Heinrich (Laudenbach, DE)
Assignee: Roche Diagnostics GmbH (Mannheim, DE)
Application Number:09/147,149
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,143,326
Patent Claims: 1. A method of treating a bone disease in a patient in need thereof, comprising orally administering to the patient a pharmaceutical formulation comprising a tablet core containing about 0.1 to 100 mg of ibandronate and a coating which is free of ibandronate and has the following proportional composition:

(a) about 51.425% by weight of methylhydroxypropylcellulose;

(b) about 24.650% by weight of titanium dioxide;

(c) about 15.000% by weight of polyethylene glycol; and

(d) about 8.925% by weight of talc.

2. The method of claim 1, wherein the bone disease is related to a disorder in calcium metabolism.

3. The method of claim 1, wherein the bone disease is selected from the group consisting of hypercalcemia, osteoporosis, tumor osteolysis, and Paget's disease.

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