Last Updated: May 15, 2026

Claims for Patent: 6,133,260


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Summary for Patent: 6,133,260
Title:Use of 7-(2-oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-quinolone carboxylic acid and naphthyridon carboxylic acid derivatives for the treatment of Helicobacter pylori infections and associated gastroduodenal diseases
Abstract:The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a 2-oxa-5,8-diazabicyclo[4.3.0]-non-8-yl) radical, and their pharmaceutically utilizable hydrates and/or salts for the therapy of Helicobacter pylori infections and the gastroduodenal disorders associated therewith.
Inventor(s):Michael Matzke, Uwe Petersen, Thomas Jaetsch, Stephan Bartel, Thomas Schenke, Thomas Himmler, Bernd Baasner, Hans-Otto Werling, Klaus Schaller, Harald Labischinski
Assignee: Bayer Intellectual Property GmbH
Application Number:US09/319,888
Patent Claims: 1. A compound which is 8-cyano-1-cyclopropyl-6-fluoro-7-((1S,6S)-2-oxa-5,8-diazabicyclo [4.3.0]-non-8-yl)-1,4-dihydro-4-oxo-3-quinoline carboxylic acid of the formula: ##STR43## or a pharmaceutically utilizable hydrate and/or salt thereof.

2. A pharmaceutical composition comprising the compound according to claim 1 and a pharmaceutically utilizable carrier.

3. A method for treating a Helicobacter pylori infection and/or a gastroduodenal disorder associated with a Helicobacter pylori infection, said method comprising administering to a patient an effective amount therefor of the compound according to claim 1.

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