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Last Updated: December 12, 2025

Claims for Patent: 6,110,918

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Summary for Patent: 6,110,918

Title:	Mesylate trihydrate salt of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihy dro-2(1H)-indol-2-one (=ziprasidone), its preparation and its use as dopamine D2 antagonist
Abstract:	PCT No. PCT/IB97/00306 Sec. 371 Date Mar. 2, 1999 Sec. 102(e) Date Mar. 2, 1999 PCT Filed Mar. 26, 1997 PCT Pub. No. WO97/42190 PCT Pub. Date Nov. 13, 1997Mesylate Trihydrate Salt of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2(1H)-indol-2-one (=Ziprasidone), Its Preparation and Its Use as Dopamine D2 Antagonist The invention relates to the mesylate trihydrate salt of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2(1H)-indol-2-one ("ziprasidone mesylate trihydrate"), to pharmaceutical compositions containing ziprasidone mesylate trihydrate, and to methods of administering ziprasidone mesylate trihydrate to treat psychotic diseases.
Inventor(s):	Frank R. Busch, Carol A. Rose
Assignee:	Pfizer Inc
Application Number:	US09/180,456
Patent Claims:

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