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Generated: September 24, 2017

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Title: Bisulfate salt of HIV protease inhibitor
Abstract:The present invention provides the crystalline bisulfate salt of the formula ##STR1## which is found to have unexpectedly high solubility/dissolution rate and oral bioavailability relative to the free base form of this azapeptide HIV protease inhibitor compound.
Inventor(s): Singh; Janak (Lawrenceville, NJ), Pudipeddi; Madhusudhan (Plainsboro, NJ), Lindrud; Mark D. (Basking Ridge, NJ)
Assignee: Bristol-Myers Squibb Company (Princeton, NJ)
Application Number:09/217,538
Patent Claims: 1. The bisulfate salt having the formula ##STR5##

2. A pharmaceutical dosage form comprising the bisulfate salt of claim 1 and a pharmaceutically acceptable carrier.
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Merck

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