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Last Updated: December 11, 2025

Claims for Patent: 6,060,085

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Summary for Patent: 6,060,085

Title:	Compositions and methods for topical application of therapeutic agents
Abstract:	The present invention generally relates to pharmaceutical compositions that enable control of drug delivery properties and the development of optimal drug delivery strategies customized for particular drugs and particular diseases. The composition includes a dissolved pharmaceutical that has the capacity to permeate the stratum corneum layer of the epidermis and become available systemically, and a pharmaceutical in a microparticulate state that does not readily cross the stratum corneum of the epidermis. The dissolved and microparticulate pharmaceuticals may be the same or different pharmaceuticals. Methods for the preparation and use of the compositions are also provided. In a preferred embodiment, the invention finds particular use in a formulation for the topical application of dapsone for the treatment of acne. In another preferred embodiment, the invention finds particular use for the treatment of herpes lesions.
Inventor(s):	David W. Osborne
Assignee:	Allergan Inc
Application Number:	US09/201,521
Patent Claims:

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