Get our Free Drug Patent Expiration Updates

Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Cantor Fitzgerald

Generated: November 17, 2018

DrugPatentWatch Database Preview

Claims for Patent: 6,057,305

« Back to Dashboard

Summary for Patent: 6,057,305
Title: Antiretroviral enantiomeric nucleotide analogs
Abstract:Resolved enantiomers of the formula ##STR1## wherein B is a purine or pyrimidine base or aza and/or deaza analogs thereof are useful in antiviral pharmaceutical compositions to treat retroviral infections.
Inventor(s): Holy ; Antonin (Praha, CS), Dvorakova ; Hana (Praha, CS), DeClercq; Erik Desire Alice (Lovenjoel, BE), Balzarini; Jan Marie Rene (Heverlee, BE)
Assignee: Institute of Organic Chemistry and Biochemistry of the Academy of (CZ) Rega Stichting, v.z.w. (BE)
Application Number:07/925,610
Patent Claims: 1. A method of achieving a human immunodeficiency virus or hepatitus B virus antiviral effect in a mammal in need of such treatment which comprises administering to said mammal an antivirally effective amount of a compound of the formula ##STR13## including physiologically acceptable salts of such compound, wherein said compound of Formula IA is the R isomer substantially free of its enantiomer and wherein B is a purine moiety substituted at the 6 position by amino, alkylamino, dialkylamino, or aralkylamino, and wherein R is H, and wherein alkyl is straight or branched chain C1-C6, aryl is a C6-C10 aromatic group, and aralkyl is a C1-C6 straight or branched chain alkyl-C6-C10 aromatic group.

2. The method of claim 1 wherein the antiviral compound is 9-(R)-(2-phosphonomethoxypropyl)adenine.

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Federal Trade Commission
Argus Health
US Army
Johnson and Johnson
Chinese Patent Office
Queensland Health

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.