Claims for Patent: 6,039,931

Summary for Patent: 6,039,931

Title:	Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
Abstract:	Compounds of general Formula I ##STR1## wherein Z1 and Z2 in each case independently mean the residue --(CH.sub.2).sub.m --(C.sub.6 H.sub.4).sub.q --(O).sub.k --(CH.sub.2).sub.n --(C6 H4)l --(O)r --R, wherein m and n means the numbers 0-20, k, l, q and r means the numbers 0 and 1, and R means a hydrogen atom, an optionally OR1 -substituted C1 -C6 -alkyl residue, or a CH2 COOR1 group with R1 meaning it hydrogen atom, a C1 -C6 -alkyl residue, or a benzyl group, X means a hydrogen atom and/or a metal ion equivalent of an element of atomic number 21-29, 42, 44 or 57-83, with the provisos that at least two the substituents X stand for a metal ion equivalent; that one of the substituents Z1 and Z2 stands for a hydrogen and the other is not H; that--if n and l each mean the number 0--k and r do not simultaneously mean the number 1; that --(O)r --R is not --OH; and that Z1 and Z2 are not --CH2 --C6 H4 --O--CH2 --COOCH2 C6 H5 or --CH2 --C6 H4 --O--(CH2)5 --COOCH2 C6 H5, as well as their salts with inorganic and/or organic bases, amino acids or amino acid amides, are valuable pharmaceutical agents, e.g., for NMR.
Inventor(s):	Heribert Schmitt-Willich, Johannes Platzek, Heinz Gries, Gabrielle Schumann-Giampieri, Hanns-Joachim Weinmann, Hubert Vogler, Julius Deutsch, Juergen Conrad
Assignee:	Bayer Intellectual Property GmbH
Application Number:	US08/319,357
Patent Claims: