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Last Updated: April 19, 2024

Claims for Patent: 6,013,657

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Summary for Patent: 6,013,657

Title:	Pharmaceutical compositions containing mupirocin
Abstract:	The invention provides a chemically stable composition comprising a therapeutically effective amount of mupirocin, in a carrier selected from the group consisting of oleyl alcohol, castor oil and a mixture thereof, the composition further optionally comprising a pharmaceutically acceptable base.
Inventor(s):	Lavon; Ilana (Beer-Sheva, IL), Abu-Gnim; Chalil (Beer-Sheva, IL), Zeevi; Amira (Omer, IL), Raechav; Yoav (Beer-Sheva, IL), Katz; Shifra (Beer-Sheva, IL), Kaspi; Joseph (Givatayim, IL)
Assignee:	AGIS Industries Ltd. (IL)
Application Number:	09/111,554
Patent Claims:	1. A chemically stable composition comprising a therapeutically effective amount of mupirocin, in a carrier selected from the group consisting of oleyl alcohol, castor oil and a mixture thereof, said composition further optionally comprising a pharmaceutically acceptable base. 2. A composition according to claim 1, further optionally comprising other pharmaceutically acceptable additives. 3. A composition according to claim 2, wherein the pharmaceutical additives are hydrophobic and/or hydrophilic surfactants. 4. A composition according to claim 3, wherein the hydrophobic surfactant is propylene glycol stearate. 5. A composition according to claim 3, wherein the hydrophilic surfactant is a sucrose ester. 6. A composition according to claim 5, wherein the sucrose ester is chosen from sucrose stearate, sucrose palmitate, sucrose oleate and sucrose myristate. 7. A composition according to claim 1, comprising from 1 to 99% of castor oil. 8. A composition according to claim 1, comprising from 1 to 99% of oleyl alcohol. 9. A composition according to claim 1, comprising a mixture of castor oil and oleyl alcohol. 10. A composition according to claim 1, wherein said base is a hard fat ointment base. 11. A composition according to claim 10, wherein the concentration of the hard fat is between 10% and 90%. 12. A drop formulation according to claim 1 which comprises 1-5% mupirocin dissolved in castor oil.

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